Uxbridge () is a suburban town in west London and the administrative headquarters of the London Borough of Hillingdon. Situated 15.4 miles (24.8 km) west-northwest of Charing Cross, it is one of the major metropolitan centres identified in the London Plan. Uxbridge formed part of the parish of Hillingdon in the county of Middlesex, and was a significant local commercial centre from an early time. As part of the suburban growth of London in the 20th century it expanded and increased in population, becoming a municipal borough in 1955, and has formed part of Greater London since 1965.

A few major events have taken place in and around the town, including attempted negotiations between King Charles I and the Parliamentary Army during the English Civil War. The public house at the centre of those events, since renamed the Crown & Treaty, still stands. RAF Uxbridge houses the Battle of Britain Bunker, from where the air defence of the south-east of England was coordinated during the Battle of Britain especially from its No. 11 Group Operations Room, also used during the D-Day landings.

Today the town serves as a significant retail and commercial centre; it is also considered as a university town as it houses Brunel University London as well as the Uxbridge campus of Buckinghamshire New University. A part of the town which has large converted flour mills adjoins Buckinghamshire, the boundary being the River Colne.

Government data analysts have confirmed within its Borough are suburbs Harefield, Ickenham, Hillingdon, Newyears Green and Cowley; with Uxbridge these are represented by six electoral wards (units for the election of councillors to Hillingdon Council and commonly for statistical purposes). The 2011 Census recorded a population figure of 70,560 for these wards combined.